Cannabis and Cannabinoids (PDQ®)–Health Professional Version

Overview This cancer information summary provides an overview of the use of Cannabis and its components as a treatment for people with cancer-related symptoms caused by the disease itself or its treatment. This summary contains the following key information: Cannabis has been used for medicinal purposes for thousands of years. By federal law, the possession of Cannabis is illegal in the United States, except […]

Uncovering the hidden antibiotic potential of Cannabis

Abstract The spread of antimicrobial resistance continues to be a priority health concern worldwide, necessitating exploration of alternative therapies. Cannabis sativa has long been known to contain antibacterial cannabinoids, but their potential to address antibiotic resistance has only been superficially investigated. Here, we show that cannabinoids exhibit antibacterial activity against MRSA, inhibit its ability to form biofilms […]

Antibacterial cannabinoids from Cannabis sativa: a structure-activity study

Abstract Marijuana (Cannabis sativa) has long been known to contain antibacterial cannabinoids, whose potential to address antibiotic resistance has not yet been investigated. All five major cannabinoids (cannabidiol (1b), cannabichromene (2), cannabigerol (3b), Delta (9)-tetrahydrocannabinol (4b), and cannabinol (5)) showed potent activity against a variety of methicillin-resistant Staphylococcus aureus (MRSA) strains of current clinical relevance. […]

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